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Internationally, there are currently five centers planned or under construction China, France, Japan, South Korea, and Taiwan 4. Furthermore, although not extensively studied, there is likely a high medical need for CIRT in the United States, similar to in Korea or Iran , Given the promising early clinical data as well as the advantages of heavy ion therapy, our institution recently announced the intent to construct a heavy ion facility in Jacksonville, Florida.

By opening the heavy ion facility, we hope to further research the potential benefits of CIRT. Taking advantage of the unique radiobiological and physical properties, CIRT is a promising treatment technique in the treatment of a variety of malignancies. Extensive further prospective trials are needed to define the role of carbon ion therapy in clinical practice. TM and DT: conception and design. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Results of a combination treatment with intensity modulated radiotherapy and active raster-scanning carbon ion boost for adenoid cystic carcinoma of the minor salivary glands of the nasopharynx. Oral Oncol. Salvage treatment using carbon ion radiation in patients with locoregionally recurrent nasopharyngeal carcinoma: initial results. Chin J Cancer. Feasibility of carbon ion radiotherapy for locally advanced sinonasal adenocarcinoma.

A retrospective multicenter study of carbon-ion radiotherapy for external auditory canal and middle ear carcinomas. Cancer Med. Carbon ion radiotherapy for locally advanced squamous cell carcinoma of the external auditory canal and middle ear.

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